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MTA1 Antibody

CAT: 0223-60-671Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-671Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq].
NCBI Gene ID
9112
Swiss Prot
Q13330
Accession Number
Q13330
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MTA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human MTA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
81 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MTA1
NCBI Official Name
Metastasis-associated protein MTA1
NCBI Organism
Homo sapiens
Background Reference 01
Zhu, X., et al.Thorac Oncol 5 (8) :1159-1166 (2010)
Background Reference 02
Van Rechem, C., et al. Mol. Cell. Biol. 30 (16) :4045-4059 (2010)
Background Reference 03
Yang, Y.M., et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 26 (7) :682-684 (2010)
Background Reference 04
Li, D.Q., et al. J. Biol. Chem. 285 (26) :19802-19812 (2010)
Other Product Names
Metastasis-associated protein MTA1, MTA1
Tested Applications
WB
Protein ID
259016275
Physical Properties
Liquid

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