CHFR Antibody

• Background :

  This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.

• NCBI Gene ID :

  55743

• Swiss Prot :

  Q96EP1

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CHFR (NP_001154818.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  Affinity purification

• Positive Control :

  HT-1080

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 70kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  CHFR

• Positive Control 2 :

  22Rv1

• Positive Control 3 :

  HepG2

• Positive Control 4 :

  Mouse kidney

• Positive Control 5 :

  Mouse testis

• NCBI Official Name :

  Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CHFR, FLJ10796, FLJ33629, RNF116, RNF196

• Tested Applications :

  WB

• Physical Properties :

  Liquid