CHFR Antibody

• Background:

  This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.

• NCBI Gene ID:

  55743

• Swiss Prot:

  Q96EP1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CHFR (NP_001154818.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  HT-1080

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CHFR

• Positive Control 2:

  22Rv1

• Positive Control 3:

  HepG2

• Positive Control 4:

  Mouse kidney

• Positive Control 5:

  Mouse testis

• NCBI Official Name:

  Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CHFR, FLJ10796, FLJ33629, RNF116, RNF196

• Tested Applications:

  WB

• Physical Properties:

  Liquid