PLB1 Antibody

• Background :

  This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.

• NCBI Gene ID :

  151056

• Swiss Prot :

  Q6P1J6

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  A-431

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 170kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  PLB1

• Positive Control 2 :

  U-87MG

• Positive Control 3 :

  HL-60

• Positive Control 4 :

  HT-29

• Positive Control 5 :

  Mouse testis

• Positive Control 6 :

  Mouse lung

• NCBI Official Name :

  Phospholipase B1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PLB, PLB/LIP, phospholipase B1, membrane-associated, lysophospholipase, phospholipase A2, phospholipase B/lipase

• Tested Applications :

  WB

• Physical Properties :

  Liquid