CABLES1 Antibody

• Background:

  This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127) .Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  91768

• Swiss Prot:

  Q8TDN4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CABLES1 (NP_612384.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  MCF7

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 67kDa

• Fragment:

  IgG

• Symbol:

  CABLES1

• Positive Control 2:

  HT-29

• Positive Control 3:

  A-549

• Positive Control 4:

  HL-60

• Positive Control 5:

  HeLa

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Cdk5 and Abl enzyme substrate 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CABL1, CABLES, HsT2563, IK3-1, CDK5 and ABL1 enzyme substrate 1, interactor with CDK3 1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid