H3F3B Antibody

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17.

• NCBI Gene ID:

  3021

• Swiss Prot:

  P84243

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human H3F3B (NP_002098.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 15kDa

• Fragment:

  IgG

• Symbol:

  H3F3B

• Positive Control 2:

  SW620

• Positive Control 3:

  U-87MG

• Positive Control 4:

  MCF7

• Positive Control 5:

  LO2

• NCBI Official Name:

  H3 histone family member 3B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  H3.3B, histone H3.3, H3 histone, family 3B (H3.3B)

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid