NACA Antibody

CAT: 223-13-442Size: 100 µLDry Ice: NoHazardous: No
100 µLSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC) . This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
NCBI Gene ID
4666
Swiss Prot
Q13765
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human NACA (NP_001106673.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HL-60
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Symbol
NACA
Positive Control 2
SW620
Positive Control 3
293T
Positive Control 4
U-87MG
Positive Control 5
HeLa
Positive Control 6
Mouse liver
NCBI Official Name
Nascent polypeptide associated complex subunit alpha
NCBI Organism
Homo sapiens
Other Product Names
HSD48, NAC-alpha1, skNAC, NACA, nascent polypeptide-associated complex subunit alpha, alpha-NAC, muscle-specific form, nascent-polypeptide-associated complex alpha polypeptide
Tested Applications
WB, IHC, IP
Physical Properties
Liquid