LAIR1 Antibody

• Background:

  The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  3903

• Swiss Prot:

  Q6GTX8

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human LAIR1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  Affinity purification

• Positive Control:

  B cells

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 35kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:1000 - 1:4000

• Symbol:

  LAIR1

• Positive Control 2:

  Jurkat

• Positive Control 3:

  HL-60

• Positive Control 4:

  Raji

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Leukocyte-associated immunoglobulin-like receptor 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  LAIR1, leukocyte-associated immunoglobulin-like receptor 1, leukocyte-associated Ig-like receptor 1, LAIR-1, CD305

• Tested Applications:

  WB

• Physical Properties:

  Liquid