LAIR1 Antibody

• Background:

  The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.

• NCBI Gene ID:

  3903

• Swiss Prot:

  Q6GTX8

• Accession Number:

  Q6GTX8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human LAIR1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  LAIR1

• NCBI Official Name:

  Leukocyte-associated immunoglobulin-like receptor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 02:

  Brondijk, T.H., et al. Blood 115 (7) :1364-1373 (2010)

• Background Reference 03:

  Tang, X., et al. J. Immunol. 182 (9) :5446-5452 (2009)

• Background Reference 04:

  Lebbink, R.J., et al. Matrix Biol. 28 (4) :202-210 (2009)

• Other Product Names:

  Leukocyte-associated immunoglobulin-like receptor 1, LAIR-1, hLAIR1, CD305, LAIR1, CD305

• Tested Applications:

  WB

• Protein ID:

  74736490

• Physical Properties:

  Liquid