PPAR gamma Antibody

• Background:

  This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

• NCBI Gene ID:

  5468

• Swiss Prot:

  P37231

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 50-150 of human PPAR gamma (NP_056953.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Obesity, Signal Transduction, Stem Cell, Transcription

• Purification:

  Affinity purification

• Positive Control:

  SKOV3

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 57kDa

• Fragment:

  IgG

• Symbol:

  PPARG

• Positive Control 2:

  THP-1

• Positive Control 3:

  SW620

• Positive Control 4:

  Mouse kidney

• NCBI Official Name:

  Peroxisome proliferator-activated receptor gamma

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PPARG, GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid