TH Antibody

• Background:

  The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

• NCBI Gene ID:

  7054

• Swiss Prot:

  P07101

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TH (NP_954986.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 59kDa

• Fragment:

  IgG

• Symbol:

  TH

• Positive Control 2:

  Rat brain

• NCBI Official Name:

  Tyrosine hydroxylase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  TH, tyrosine hydroxylase, HGNC:11782, TYH, DYT14, DYT5b, dystonia 14, tyrosine 3-monooxygenase

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid