SUSD3 Antibody

CAT: 0223-8475-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-8475-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha) -positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2) . Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3) . Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3) .
NCBI Gene ID
203328
Swiss Prot
Q96L08
Accession Number
NP_659443
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cancer
Purification
SUSD3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1282 - 3T3 (NIH) Cell Lysate
Concentration
1 mg/mL
Buffer
SUSD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SUSD3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.
Symbol
SUSD3
Positive Control 2
Cat. No. 17-201 - 3T3/BALB Cell Slide
NCBI Official Name
Sushi domain containing 3
NCBI Organism
Homo sapiens
Background Reference 01
Abba MC, Hu Y, Sun H, et al. Gene expression signature of estrogen receptor alpha status in breast cancer. BMC Genomics 2005; 6:37.
Background Reference 02
Parris TZ, Danielsson A, Nemes S, et al. Clinical implications of gene dosage and gene expression patterns in diploid breast cancer. Clin. Cancer Res. 2010; 16:3860-74.
Background Reference 03
Moy I, Todorovic V, Dubash AD, et al. Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells. Oncogene 2015; 34:323-33.
Other Product Names
Sushi domain containing 3
Tested Applications
ELISA, WB, ICC
Protein ID
21450717
Physical Properties
Liquid

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