LANCL2 Antibody

CAT: 0223-8369-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-8369-01Size:0.02 mg
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Background
LANCL2 (LanC-like protein 2), also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1) . It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2,3) . LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3,4) .
NCBI Gene ID
55915
Swiss Prot
Q9NS86
Accession Number
NP_061167
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
LANCL2 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
LANCL2 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
LANCL2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
LANCL2 antibody is human, mouse and rat reactive.
Symbol
LANCL2
NCBI Official Name
LanC lantibiotic synthetase component C-like 2 (bacterial)
NCBI Organism
Homo sapiens
Background Reference 01
Mayer H, Pongratz M, and Prohaska R. Molecular cloning, characterization, and tissue-specific expression of human LANCL2, a novel member of the LanC-like protein family. DNA Seq. 2001; 12:161-6.
Background Reference 02
Sturla L, Fresia C, Guida L, et al. Binding of abscisic acid to human LANCL2. Biochem. Biophys. Res. Commun. 2011; 415:390-5.
Background Reference 03
Landlinger C, Salzer U, and Prohaska R. Myristoylation of human LanC-like protein 2 (LANCL2) is essential for the interaction with the plasma membrane and the increase in cellular sensitivity to adriamycin. Biochim. Biophys. Acta. 2006; 1758:1759-67.
Background Reference 04
Zeng M, van der Donk WA, Chen J. Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. Mol. Biol. Cell 2014; 25:3954-61.
Other Product Names
LanC lantibiotic synthetase component C-like 2, GPR69B, LanC-like protein 2, TASP, Testis-specific adriamycin sensitivity protein
Tested Applications
ELISA, WB, IHC-P
Protein ID
8923911
Physical Properties
Liquid

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