CDO1 Antibody

CAT: 0223-8137-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-8137-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis (1) . CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine (1,2) . CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart (1) . CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell (3,4) .
NCBI Gene ID
1036
Swiss Prot
Q16878
Accession Number
NP_001792
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
CDO1 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1464 - Rat Liver Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (84%)
Buffer
CDO1 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CDO1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
CDO1 antibody is human, mouse and rat reactive.
Symbol
CDO1
NCBI Official Name
Cysteine dioxygenase type 1
NCBI Organism
Homo sapiens
Background Reference 01
McCann KP, Akbari MT, Williams AC, et al. Human cysteine dioxygenase type I: primary structure derived from base sequencing of cDNA. Biochim. Biophys. Acta 1994; 1209:107-10.
Background Reference 02
Ye S, Wu X, Wei L, et al. An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor. J. Biol. Chem. 2007; 282:3391-402.
Background Reference 03
Booken N, Gratchev A, Utikal J, et al. Sezary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3. Leukemia 2008; 22:393-9.
Background Reference 04
Wrangle J, Machida EO, Danilova L, et al. Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer. Clin. Cancer Res. 2014; 20:1856-64.
Other Product Names
Cysteine dioxygenase type I, CDO, CDO-I, Cysteine dioxygenase type 1
Tested Applications
ELISA, WB
Protein ID
56786147
Physical Properties
Liquid

Related Products

CatalogName
8137PCDO1 Peptide
16-263CDON Antibody
42-168CDO Antibody
42-168PCDO Peptide
91-606Brother of CDO Recombinant Protein
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
63-408DGKB Antibody
63-412AK5 Antibody

Alternative Products

CatalogName
C42989-01CDO1 Antibody

Popular Products