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SKI2W Antibody

CAT: 0223-7993-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7993-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2) . SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2) . The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4) .
NCBI Gene ID
6499
Swiss Prot
Q15477
Accession Number
NP_008860
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
SKI2W antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1415 - Mouse Stomach Tissue Lysate
Concentration
1 mg/mL
Buffer
SKI2W antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SKI2W antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist; this antibody will detect both isoforms.
Symbol
SKIV2L
Positive Control 2
Cat. No. 10-801 - Human Stomach Tissue Slide
NCBI Official Name
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Dangel AW, Shen L, Mendoza AR, et al. Human helicase gene SKI2W in the HLA class III region exhibits striking structural similarities to the yeast antiviral gene SKI2 and to the human gene KIAA0052: emergence of a new gene family. Nucleic Acids Res. 1995; 23:2120-6.
Background Reference 02
Qu X, Yang Z, Zhang S, et al. The human DEVH-box protein Ski2w from the HLA is localized in nucleoli and ribosomes. Nucleic Acids Res. 1998; 26:4068-77.
Background Reference 03
Yang Z, Shen L, Dangel AW, et al. Four ubiquitously expressed genes, RD (D6S45) -SKI2W (SKIV2L) -DOM3Z-RP1 (D6S60E), are present between complement component genes factor B and C4 in the class III region of the HLA. Genomics 1998; 53:338-47.
Background Reference 04
Yang Z, Qu X, and Yu CY. Features of the two gene pairs RD-SKI2W and DOM3Z-RP1 located between complement component genes factor B and C4 at the MHC class III region. Front. Biosci. 2001; 6:D927-35.
Other Product Names
Superkiller viralicidic activity 2-like, DDX13, Helicase-like protein, Helicase SKI2W, HLP, SKI2, SKIV2, SKIV2L
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
67782311
Physical Properties
Liquid

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