DAF Antibody

CAT: 0223-7937-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-7937-01Size:0.02 mg
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Background
The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1) . DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2) . Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3) .
NCBI Gene ID
1604
Swiss Prot
P08174
Accession Number
NP_001108224
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
DAF antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1203 - A549 Cell Lysate
Concentration
1 mg/mL
Buffer
DAF antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DAF antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
DAF antibody is human specific. At least two isoforms of DAF are known to exist; this antibody will only detect the longest isoform.
Symbol
CD55
Positive Control 2
Cat. No. 10-101 - Human Lung Tissue Slide
Positive Control 3
Cat. No. 1201 – HeLa Cell Lysate
NCBI Official Name
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
NCBI Organism
Homo sapiens
Background Reference 01
Nicholson-Weller A, March JP, Rosen CE, et al. Surface membrane expression by human blood leukocytes and platelts of decay-accelerating factor, a regulatory protein of the complement system. Blood 1985; 65:1237-44.
Background Reference 02
Seya T and Atkinson JP. Functional properties of membrane cofactor protein of complement. Biochem. J. 1989; 64:581-8.
Background Reference 03
Storry JR, Reid ME, and Yazer MH. The Cromer blood group system: a review. Immunohematology 2010; 109-18.
Other Product Names
Decay-accelerating factor, CD55 molecule decay accelerating factor for complement (Cromer blood group), CD55, CR, TC, CROM
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
168693643
Physical Properties
Liquid

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