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UBIAD1 Antibody

CAT: 0223-7751-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7751-01Size:0.02 mg
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Background
The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1) . Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2) . Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3) .
NCBI Gene ID
29914
Swiss Prot
Q9Y5Z9
Accession Number
NP_037451
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
UBIAD1 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1404 - Mouse Liver Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Chicken: (87%)
Buffer
UBIAD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
UBIAD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
UBIAD1 antibody is human, mouse and rat reactive.
Symbol
UBIAD1
NCBI Official Name
UbiA prenyltransferase domain containing 1
NCBI Organism
Homo sapiens
Background Reference 01
McGarvey TW, Nguyen T, Tomaszewski JE, et al. Isolation and characterization of TERE1 gene, a gene down-regulated in transitional cell carcinoma of the bladder. Oncogene 2001; 20:1042-51.
Background Reference 02
Fredericks WJ, McGarvey T, Wang H, et al. The bladder tumor suppressor protein TERE1 (UBIAD1) modulates cell cholesterol: implications for tumor progression. DNA Cell Biol. 2011; 30:851-64.
Background Reference 03
Orr A, Dube MP, Marcadier J, et al. Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy. PLoS One 2007; 2:e685.
Other Product Names
UBIAD1 Antibody: SCCD, TERE1, UbiA prenyltransferase domain-containing protein 1, Transitional epithelial response protein 1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
7019551
Physical Properties
Liquid

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