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ADROPIN Antibody

CAT: 0223-7527-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7527-01Size:0.02 mg
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Background
ADROPIN is a recently identified protein that has been implicated in the maintenance of energy homeostasis and insulin resistance (1-3) . ADROPIN expression is regulated by energy status and dietary nutrient content and is altered by obesity and regulates the expression of hepatic lipogenic genes and adipose tissue peroxisome proliferator-activated receptor gamma (PPAR-gamma) (1) . ADROPIN levels increase with dietary fat content (2) . ADROPIN has also been proposed to play a role in the regulation of endothelial function (3) .
NCBI Gene ID
375704
Swiss Prot
Q6UWT2
Accession Number
NP_940975
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Purification
ADROPIN antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Buffer
ADROPIN antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ADROPIN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
ADROPIN antibody is human, mouse and rat reactive. Despite its predicted molecular weight, ADROPIN often migrates at a higher than expected molecular weight in SDS-PAGE.
Symbol
ENHO
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
Energy homeostasis associated
NCBI Organism
Homo sapiens
Background Reference 01
Kumar KG, Trevaskis JL, Lam DD, et al. Identification of Adropin as a secreted factor linking dietary macronutrient intake with energy homeostasis and lipid metabolism. Cell Metab. 2008; 8:468-81.
Background Reference 02
Kumar KG, Zhang J, Gao S, et al. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity 2012; 1394-402.
Background Reference 03
Lovren F, Pan Y, Quan A, et al. Adropin is a novel regulator of endothelial function. Circulation 2010; 122:S185-92.
Other Product Names
ADROPIN Antibody: UNQ470, C9orf165, UNQ470/PRO830, Adropin, Energy homeostasis-associated protein
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
58218977
Physical Properties
Liquid

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