Products for Research Use Only
RegisterLogin

NCBP1 Antibody

CAT: 0223-7395-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-7395-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2) . Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways for splicing, nuclear export, and translation (3) .
NCBI Gene ID
4686
Swiss Prot
Q09161
Accession Number
NP_002477
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
NCBP1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Chicken: (81%)
Buffer
NCBP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NCBP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
NCBP1 antibody is human, mouse and rat reactive. At least two isoforms of NCBP1 are known to exist; this antibody will detect both isoforms of NCBP1.
Symbol
NCBP1
Positive Control 2
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
Nuclear cap binding protein subunit 1, 80kDa
NCBI Organism
Homo sapiens
Background Reference 01
Ohno M, Kataoka N, and Shimura Y. A nuclear cap binding protein from HeLa cells. Nuc. Acid Res. 1990; 18:6989-95.
Background Reference 02
Maquat LE, Hwang J, Sato H, et al. CBP80-promoted mRNP rearrangements during the pioneer round of translation, nonsense-mediated mRNA decay, and thereafter. Cold Spring Harbor Symp. Quant. Biol. 2010; 75:127-34.
Background Reference 03
Bier K, York A, and Fodor E. Cellular cap-binding proteins associate with influenza virus mRNAs. J. Gen. Virol. 92:1627-34.
Other Product Names
NCBP1 Antibody: NCBP, Sto1, CBP80, NCBP, Nuclear cap-binding protein subunit 1, 80 kDa nuclear cap-binding protein
Tested Applications
ELISA, WB, ICC
Protein ID
4505343
Physical Properties
Liquid

Related Products

CatalogName
7395PNCBP1 Peptide
22-841NCBP2 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody

Alternative Products

CatalogName
GWB-MN421GNCBP1 Antibody

Popular Products