Products for Research Use Only
RegisterLogin

LPIN1 Antibody

CAT: 0223-7393-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-7393-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
LPIN1 Antibody: LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1) . LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism (1,2) . Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria (3,4) and it is also a candidate for several human lipodystrophy syndromes (5) .
NCBI Gene ID
23175
Swiss Prot
Q14693
Accession Number
NP_001248357
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
LPIN1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1204 - K562 Cell Lysate
Concentration
1 mg/mL
Buffer
LPIN Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
LPIN antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Observed Molecular Weight
Other LPIN1 antibodies show similar size band
Fragment
IgG
Specificity
LPIN1 antibody is human and mouse reactive. At least four isoforms of LPIN1 are known to exist.
Symbol
LPIN1
Positive Control 2
Cat. No. 11-801 - Human Small Intestine Tissue Slide
NCBI Official Name
Lipin 1
NCBI Organism
Homo sapiens
Background Reference 01
Reue K and Zhang P. The lipin protein family: dual roles in lipid biosynthesis and gene expression. FEBS Lett. 2008; 582:90-6.
Background Reference 02
Peterfy M, Phan J, Xu P, et al. Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin. Nat. Genet. 2001; 27:121-4.
Background Reference 03
Zhang R, Jiang F, Hu C, et al. Genetic variants of LPIN1 indicate an association with Type 2 diabetes mellitus in a Chinese population. Diabet. Med. 2013; 30:118-22.
Background Reference 04
Zeharia A, Shaag A, Houtkooper RH, et al. Mutations in LPIN1 cause recurrent acute myoglobinuria in childhood. Am. J. Hum. Genet. 2008; 83:489-94.
Other Product Names
LPIN1 Antibody: PAP1, KIAA0188, Phosphatidate phosphatase LPIN1, Lipin-1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
387528013
Physical Properties
Liquid

Related Products

CatalogName
7393PLPIN1 Peptide
63-529LPIN2 Antibody
16-218LPIN2 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
13-862C19orf10 Antibody
70-833XIAP Antibody
63-833FLAD1 Antibody
58-833NEGR1 Antibody

Alternative Products

CatalogName
abx321300-01Phosphatidate Phosphatase LPIN1 (LPIN1) Antibody
MBS8517247-01LPIN1 Antibody

Popular Products