DAP Antibody

CAT: 0223-7389-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-7389-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1) . DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2) .
NCBI Gene ID
1611
Swiss Prot
P51397
Accession Number
NP_004385
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Autophagy
Purification
DAP Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1308 - Human Small Intestine Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (89%)
Buffer
DAP Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DAP antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
DAP antibody is human, mouse and rat reactive.
Symbol
DAP
Positive Control 2
Cat. No. 11-801 - Human Small Intestine Tissue Slide
NCBI Official Name
Death-associated protein
NCBI Organism
Homo sapiens
Background Reference 01
Deiss LP, Feinstein E, Berissi H, et al. Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev. 1995; 9:15-30.
Background Reference 02
Koren I, Reem E, and Kimchi A. DAP1, a novel substrate of mTOR, negatively regulates autophagy. Curr. Biol. 2010; 20:1093-8.
Other Product Names
DAP Antibody: DAP1, Death-associated protein 1, DAP-1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
4758120
Physical Properties
Liquid

Related Products

CatalogName
7389PDAP Peptide
2323PDAP kinase 2 Peptide
45-046DAP3 Antibody
22-624DAP3 Antibody
45-046PDAP3 Peptide
64-160WAS Antibody
13-349WAS Antibody
60-596WAS Antibody
7935-002mgSHBG Antibody
1105-002mgCCR3 Antibody

Alternative Products

CatalogName
MBS8513599-01CD11b Antibody Antibody
MBS8529199-01H2B Antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
DF8746-01ASAP1 antibody Antibody
E36403ZNF98 Antibody Antibody
E8M1007-4HSP60 Antibody Antibody
GWB-250026Lck antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
AN100003PPAK1 Antibody Polyclonal Antibody

Popular Products