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ERRF Antibody

CAT: 0223-7289-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-7289-01Size:0.02 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
NCBI Gene ID
149563
Swiss Prot
Q8NEQ6
Accession Number
NP_849162
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
ERRF Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Buffer
ERRF Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ERRF antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Symbol
C1orf64
Positive Control 2
Cat. No. 1288 - A20 Cell Lysate
Positive Control 3
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
Chromosome 1 open reading frame 64
NCBI Organism
Homo sapiens
Background Reference 01
Su D, Fu X, Fan S, et al. Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells. Am. J. Pathol. 2012; 180:1189-201.
Other Product Names
ERRF Antibody: ERRF, Uncharacterized protein C1orf64
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
30519894
Physical Properties
Liquid

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