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DHX36 Antibody

CAT: 0223-7163-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7163-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
NCBI Gene ID
170506
Swiss Prot
Q9H2U1
Accession Number
NP_065916
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
DHX36 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1404 - Mouse Liver Tissue Lysate
Concentration
1 mg/mL
Buffer
DHX36 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DHX36 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Calculated Molecular Weight
Predicted: 111 kDa
Fragment
IgG
Specificity
At least four isoforms of DDX36 are known to exist; this antibody will detect the three longest isoforms.
Symbol
DHX36
Positive Control 2
Cat. No. 10-201 - Human Liver Tissue Slide
NCBI Official Name
DEAH (Asp-Glu-Ala-His) box polypeptide 36
NCBI Organism
Homo sapiens
Background Reference 01
Cordin O, Banroques J, Tanner NK, et al. The DEAD-box protein family of RNA helicases. Gene 2006; 367:17-37.
Background Reference 02
Linder P. Dead-box proteins: a family affair—active and passive players in RNP-remodeling. Nucleic Acids Res. 2006; 34:4168-80.
Background Reference 03
Lattmann S, Giri B, Vaughn JP, et al. Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU. Nucleic Acids Res. 2010; 38:6219-33.
Background Reference 04
Fu JJ, Li LY, Liu SF, et al. Expression research for human DDX36 and mouse Ddx36 gene in the adult testis. Yi Chuan Xue Bao 2003; 30: 201-208.
Other Product Names
DHX36 Antibody: G4R1, RHAU, DDX36, MLEL1, KIAA1488, Probable ATP-dependent RNA helicase DHX36, DEAH box protein 36
Tested Applications
ELISA, WB, IHC-P
Protein ID
167830433
Physical Properties
Liquid

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