DHX32 Antibody

• Background:

  DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The function of this member has not been determined. Alternative splicing of this gene generates 2 transcript variants, but the full length nature of one of the variants has not been defined.

• NCBI Gene ID:

  55760

• Swiss Prot:

  Q7L7V1

• Accession Number:

  Q7L7V1

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This DHX32 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the Central region of human DHX32.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  84 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  DHX32

• NCBI Official Name:

  Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Huang, C., et al. J. Exp. Clin. Cancer Res. 28, 11 (2009) :

• Background Reference 02:

  Chen, Y., et al. Exp. Mol. Pathol. 82 (3) :256-261 (2007)

• Background Reference 03:

  Alli, Z., et al. Anticancer Res. 27 (1A), 373-377 (2007) :

• Background Reference 04:

  Alli, Z., et al. Exp. Mol. Pathol. 81 (3) :245-248 (2006)

• Other Product Names:

  Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32, DEAD/H box 32, DEAD/H helicase-like protein 1, DHLP1, DEAH box protein 32, HuDDX32, DHX32, DDX32

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74759011

• Physical Properties:

  Liquid