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DCP2 Antibody

CAT: 0223-7049-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7049-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DCP2 Antibody: The removal, or decapping, of eukaryotic mRNA is an important step in the degradation of mRNA. Decapping protein 2 (DCP2) is the major mRNA decapping enzyme in cells. It is a member of the Nudix hydrolases superfamily of proteins that predominantly catalyze the hydrolysis of small nucleoside diphosphate substrates linked to another moiety. DCP2 is widely expressed in multiple tissues at varying levels, with highest expression seen in testis and brain.
NCBI Gene ID
167227
Swiss Prot
Q8IU60
Accession Number
NP_689837
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
DCP2 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Buffer
DCP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DCP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
IgG
Specificity
Multiple isoforms of DCP2 are known to exist.
Symbol
DCP2
Positive Control 2
Cat. No. 11-701 - Human Testis Tissue Slide
NCBI Official Name
DCP2 decapping enzyme homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Song MG, Li Y, and Kiledjian M. Multiple mRNA decapping enzymes in mammalian cells. Mol. Cell 2010; 40:423-32.
Background Reference 02
Dunckley T and Parker R. The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J. 18:5411-22.
Background Reference 03
Bessman MJ, Frick DN, and O'Handley SF. The MutT proteins of “Nudix" hydrolases, a family of versatile, widely distributed, “housecleaning" enzymes. J. Biol. Chem. 1996; 271:25059-62
Other Product Names
DCP2 Antibody: NUDT20, NUDT20, m7GpppN-mRNA hydrolase, Nucleoside diphosphate-linked moiety X motif 20, Nudix motif 20
Tested Applications
ELISA, WB, IF
Protein ID
31542498
Physical Properties
Liquid

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