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SGSM3 Antibody

CAT: 0223-7037-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7037-01Size:0.02 mg
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Background
SGSM3 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. Little is known of the exact function of SGSM3.
NCBI Gene ID
27352
Swiss Prot
Q96HU1
Accession Number
CAQ08933
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
SGSM3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rat: (82%), Mouse: (82%), Bovine: (79%)
Buffer
SGSM3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SGSM3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
82 kDa
Fragment
IgG
Specificity
Multiple isoforms of SGSM3 are known to exist. SGSM3 antibody is predicted to not cross react with other SGSM family proteins.
Symbol
SGSM3
Positive Control 2
Cat. No. 17-010 - HEK293 Cell Slide
NCBI Official Name
Small G protein signaling modulator 3
NCBI Organism
Homo sapiens
Background Reference 01
Bar-Sagi D and Hall A. Ras and Rho GTPases: a family reunion. Cell 2000; 103:227-38.
Background Reference 02
Colicelli J. Human ras superfamily proteins and related GTPases. Sci. STKE 2004; 250:RE13.
Background Reference 03
Yang H, Sasaki T, Minoshima S, et al. Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB) -mediated signaling pathway. Genomics 2007; 90:249-60.
Other Product Names
SGSM3 Antibody: MAP, RUSC3, RUTBC3, RABGAP5, RabGAP-5, MAP, RABGAPLP, Small G protein signaling modulator 3, Merlin-associated protein, RabGAPLP
Tested Applications
ELISA, WB, IF
Protein ID
168985143
Physical Properties
Liquid

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