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ZFX Antibody

CAT: 0223-6811-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6811-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ZFX Antibody: The X-linked zinc finger protein ZFX is a member of the Kruppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny.
NCBI Gene ID
7543
Swiss Prot
P17010
Accession Number
NP_003401
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
ZFX Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Buffer
ZFX Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ZFX antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
ZFX antibody is human, mouse and rat reactive. Multiple isoforms of ZFX are known to exist. ZFX antibody will detect isoform 1 and 2 of ZFX.
Symbol
ZFX
Positive Control 2
Cat. No. 1223 - Caco-2 Cell Lysate
Positive Control 3
Cat. No. 11-801 - Human Small Intestine Tissue Slide
NCBI Official Name
Zinc finger protein, X-linked
NCBI Organism
Homo sapiens
Background Reference 01
Schneider-Gadicke A, Beer-Romero P, Brown LG, et al. Putative transcription activator with alternative isoforms encoded by human ZFX gene. Nature 1989; 342:708-11.
Background Reference 02
Galan-Caridad JM, Harel S, Arenzana TL, et al. Zfx controls the self-renewal of embryonic and hematopoietic stem cells. Cell 2007; 129:345-57.
Background Reference 03
Arenzana TL, Smith-Raska MR, and Reizis B. Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes. Blood 2009; 113:5857-67
Other Product Names
ZFX Antibody: ZNF926, Zinc finger X-chromosomal protein
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
71061446
Physical Properties
Liquid

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