Products for Research Use Only
RegisterLogin

SIGLEC15 Antibody

CAT: 0223-6765-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-6765-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig) -like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
NCBI Gene ID
284266
Swiss Prot
Q6ZMC9
Accession Number
NP_998767
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
SIGLEC15 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1305 - Human Kidney Tissue Lysate
Concentration
1 mg/mL
Buffer
SIGLEC15 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SIGLEC15 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
SIGLEC15 antibody is predicted to not cross-react with other SIGLEC family members.
Symbol
SIGLEC15
Positive Control 2
Cat. No. 10-401 - Human Kidney Tissue Slide
NCBI Official Name
Sialic acid binding Ig-like lectin 15
NCBI Organism
Homo sapiens
Background Reference 01
Crocker and Redelinghuys. Biochem. Soc. Trans. 2008; 36:1467-71.
Background Reference 02
Angata et al. Glycobiology 2007; 17:838-46.
Background Reference 03
Hiruma et al. Biochem. Biophys. Res. Commun. 2011; 409:424-9.
Other Product Names
SIGLEC15 Antibody: CD33L3, HsT1361, SIGLEC-15, CD33L3, Sialic acid-binding Ig-like lectin 15, CD33 antigen-like 3, Siglec-15
Tested Applications
ELISA, WB, IHC-P
Protein ID
47106069
Physical Properties
Liquid

Related Products

CatalogName
6765PSIGLEC15 Peptide
9017PSIGLEC15 Peptide
58-424SIGLEC12 Antibody
5151-002mgSiglec11 Antibody
30-597SIGLEC12 Antibody
30-596SIGLEC12 Antibody
5151-01Siglec11 Antibody
58-450SIGLEC14 Antibody
58-386SIGLEC10 Antibody
30-584SIGLEC12 Antibody

Alternative Products

CatalogName
DF13774-01SIGLEC15 Antibody

Popular Products