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NKX2-4 Antibody

CAT: 0223-6747-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6747-01Size:0.02 mg
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Background
NKX2-4 Antibody: NKX2-4 (NK2 homeobox 4) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-4 is closely related to NKX2-1 and NKX2-4 and is specifically localized to the ventral diencephalon. Recent experiments in Xenopus have suggested that the homeodomain protein XANF is necessary for the activation of NKX2-4, but does not directly regulate its expression.
NCBI Gene ID
644524
Swiss Prot
Q9H2Z4
Accession Number
NP_149416
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
NKX2-4 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1288 - A20 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Guinea pig: (100%), Rat: (86%), Chicken: (86%), Bovine: (71%)
Buffer
NKX2-4 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NKX2-4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
NKX2-4 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-4 are known to exist; this antibody will detect both isoforms.
Symbol
NKX2-4
Positive Control 2
Cat. No. 17-208 - A-20 Cell Slide
NCBI Official Name
NK2 homeobox 4
NCBI Organism
Homo sapiens
Background Reference 01
Wang CC, Brodnicki T, Copeland NG, et al. Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. Mamm. Genome 2000; 11:466-8.
Background Reference 02
Small EM, Vokes SA, Garriock RJ, et al. Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes. Mech. Dev. 2000; 96:259-62.
Background Reference 03
Hill JT, Chao CS, Anderson KR, et al. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Mol. Endocrinol. 2010; 381-90.
Other Product Names
NKX2-4 Antibody: NKX2D, NKX2.4, NKX2D, Homeobox protein NK-2 homolog D
Tested Applications
ELISA, WB, ICC, IF
Protein ID
157426823
Physical Properties
Liquid

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