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MLIP Antibody

CAT: 0223-6719-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-6719-01Size:0.02 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MLIP Antibody: The muscle-enriched A-type lamin-interacting protein (MLIP) is ubiquitously expressed, although most predominantly in heart, skeletal and smooth muscle, and interacts directly and co-localizes with lamin A and C in the nuclear envelope. MLIP also co-localizes with promyelocytic leukemia (PML) bodies within the nucleus. Decreasing lamin A/C expression with siRNA results in the upregulation and mislocalization of MLIP, suggesting that MLIP localization to the nuclear envelope is dependent on the lamin proteins. It has been suggested that MLIP may function as a tethering protein linking LMNA to factors within the nuclear envelope of within PML bodies
NCBI Gene ID
90523
Swiss Prot
Q5VWP3
Accession Number
NP_612636
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
MLIP Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Buffer
MLIP Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MLIP antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least three isoforms of MLIP are known to exist.
Symbol
MLIP
Positive Control 2
Cat. No. 10-501 - Human Heart Tissue Slide
NCBI Official Name
Muscular LMNA-interacting protein
NCBI Organism
Homo sapiens
Background Reference 01
Ahmady E, Deeke SA, Rabaa S, et al. Identification of a novel muscle A-type lamin-interacting protein (MLIP) . J. Biol. Chem. 2011; 286:19702-13.
Other Product Names
MLIP Antibody: C6orf142, C6orf142, Muscular LMNA-interacting protein, Muscular-enriched A-type laminin-interacting protein
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
154426278
Physical Properties
Liquid

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