ANKLE2 Antibody

• Background:

  ANKLE2 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE2 (Ankyrin repeat and LEM domain containing 2) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains three ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. The function of this protein is still under investigation.

• NCBI Gene ID:

  23141

• Swiss Prot:

  Q86XL3

• Accession Number:

  AAH43157

• Host:

  Chicken

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  ANKLE2 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1313 - Human Testis Tissue Lysate

• Concentration:

  1 mg/mL

• Buffer:

  ANKLE2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  ANKLE2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgY

• Specificity:

  Three isoforms of ANKLE2 are known to exist; this antibody will detect all three. ANKLE2 antibody is predicted to not cross-react with ANKLE1.

• Symbol:

  ANKLE2

• NCBI Official Name:

  Ankyrin repeat and LEM domain containing 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee KK and Wilson KL. All in the family: evidence for four new LEM-domain proteins Lem2 (NET-25), Lem3, Lem4 and Lem5 in the human genome. Symp. Soc. Exp. Biol. 2004; 56:329-39

• Other Product Names:

  ANKLE2 Antibody: Lem4, LEMD7, KIAA0692, LEM4, Ankyrin repeat and LEM domain-containing protein 2, LEM domain-containing protein 4

• Tested Applications:

  ELISA, WB

• Protein ID:

  148664230

• Physical Properties:

  Liquid