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CCDC55 Antibody

CAT: 0223-6519-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6519-01Size:0.02 mg
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Background
CCDC55 Antibody: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.
NCBI Gene ID
84081
Swiss Prot
Q9H0G5
Accession Number
NP_115517
Host
Chicken
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
CCDC55 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (88%)
Buffer
CCDC55 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CCDC55 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgY
Specificity
At least three isoforms are known to exist; this antibody will detect all three.
Symbol
NSRP1
NCBI Official Name
Nuclear speckle splicing regulatory protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Kim YD, Lee JY, Oh KM, et al. NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. Nuc. Acids Res. 2011; 39:4300-14.
Other Product Names
CCDC55 Antibody: CCDC55, NSrp70, HSPC095, CCDC55, NSRP70, Nuclear speckle splicing regulatory protein 1, Coiled-coil domain-containing protein 55
Tested Applications
ELISA, WB, IF
Protein ID
14149807
Physical Properties
Liquid

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