CCDC50 Antibody

• Background :

  CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF) -mediated cell signaling.

• NCBI Gene ID :

  152137

• Swiss Prot :

  Q8IVM0

• Accession Number :

  NP_848018

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCDC50.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  721_B Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CCDC50 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  56 kDa

• Applications Notes :

  CCDC50 antibody can be used for detection of CCDC50 by ELISA at 1:1562500. CCDC50 antibody can be used for detection of CCDC50 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  CCDC50

• NCBI Official Name :

  Coiled-coil domain containing 50

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bohgaki, M., (2008) Biochim. Biophys. Acta 1783 (5), 826-837.

• Other Product Names :

  CCDC50, C3orf6, DFNA44, YMER

• Tested Applications :

  ELISA, WB

• Protein ID :

  41281911

• Physical Properties :

  Liquid