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CCDC50 Antibody

CAT: 0223-57-583Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-583Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF) -mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
NCBI Gene ID
152137
Swiss Prot
Q8IVM0
Accession Number
Q8IVM0
Host
Rabbit
Reactivity
Human
Immunogen
This CCDC50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human CCDC50.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Symbol
CCDC50
NCBI Official Name
Coiled-coil domain-containing protein 50
NCBI Organism
Homo sapiens
Background Reference 01
Farfsing, A., et al. Leukemia 23 (11) :2018-2026 (2009)
Background Reference 02
Kameda, H., et al. Biochem. Biophys. Res. Commun. 378 (4) :744-749 (2009)
Background Reference 03
Bohgaki, M., et al. Biochim. Biophys. Acta 1783 (5) :826-837 (2008)
Background Reference 04
Modamio-Hoybjor, S., et al. Am. J. Hum. Genet. 80 (6) :1076-1089 (2007)
Other Product Names
Coiled-coil domain-containing protein 50, Protein Ymer, CCDC50, C3orf6
Tested Applications
WB, IHC-P
Protein ID
73619722
Physical Properties
Liquid

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