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FCHSD1 Antibody

CAT: 0223-6509-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6509-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FCHSD1 Antibody: The FCH and double SH3 domains protein 1 (FCHSD1, also known as NWK2) and the related protein FCHSD2 were initially identified in silico as distantly related proteins to FNBP1 and FNBP2. Both share the common domain structure consisting of FCH, FBH, two SH3 and C-terminal proline-rich domains. While little is known of the function of FCHSD1, the related protein NWK is an adaptor protein that is thought to regulate Rho activity downstream of Robo receptors, suggesting that FCHSD1 may be involved in synaptic morphology by regulating actin dynamics in presynaptic terminals.
NCBI Gene ID
89848
Swiss Prot
Q86WN1
Accession Number
NP_258260
Host
Chicken
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
FCHSD1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1219 - MCF7 Cell Lysate
Concentration
1 mg/mL
Buffer
FCHSD1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
FCHSD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgY
Specificity
Multiple isoforms of FCHSD1 are known to exist. FCHSD1 antibody is predicted to not cross-react with FCHSD2
Symbol
FCHSD1
NCBI Official Name
FCH and double SH3 domains 1
NCBI Organism
Homo sapiens
Background Reference 01
Kato M and Kato M. Identification and characterization of human FCHSD1 and FCHSD2 genes in silico. Int. J. Mol. Med. 2004; 13:749-54.
Background Reference 02
Coyle IP, Koh YH, Lee WC, et al. Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in drosophila. Neuron 2004; 41:521-34
Other Product Names
FCHSD1 Antibody: NWK2, FCH and double SH3 domains protein 1
Tested Applications
ELISA, WB
Protein ID
28875786
Physical Properties
Liquid

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