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ATAD3A Antibody

CAT: 0223-6387-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6387-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ATAD3A Antibody: ATAD3A is a member of the AAA ATPase family, a family of proteins that catalyze ATP into ADP and are involved in several cellular functions such as cell-cycle regulation, protein proteolysis and transport. The AAA ATPase family is characterized by a highly conserved AAA motif containing Walker homology sequences and imparting ATPase activity. Mitochondrial membrane proteins ATAD3A/B contribute to the stabilization of nucleoids and may participate in the transformation pathway and the chemosensitivity of oligodendrogliomas. The gene encoding ATAD3A/B/C maps to human chromosome 1 and has been suggested to be an anti-apoptotic marker.
NCBI Gene ID
55210
Swiss Prot
Q9NVI7
Accession Number
Q9NVI7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
ATAD3A Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1224 - Daudi Cell Lysate
Concentration
1 mg/mL
Buffer
ATAD3A Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ATAD3A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
ATAD3A antibody is predicted to not cross-react with other ATAD protein family members. At least two isoforms are known to exist.
Symbol
ATAD3A
NCBI Official Name
ATPase family, AAA domain containing 3A
NCBI Organism
Homo sapiens
Background Reference 01
Patel S and Latterich M. The AAA team: related ATPases with diverse functions. Trends Cell Biol. 1998; 8:65-71.
Background Reference 02
Ogura T and Wilkinson AJ. AAA+ superfamily ATPases: common structure—diverse function. Genes Cells 2001; 6:575-97.
Background Reference 03
Hubstenberger A, Labourdette G, Baudier J, et al. ATAD3A and ATAD3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties. Exp. Cell Res. 2008; 314:2870-83.
Background Reference 04
Fang HY, Chang CL, Hsu SH, et al. ATPase family AAA domain-containing 3A is a novel anti-apoptotic factor in lung adenocarcinoma cells. J. Cell Sci. 2010; 123:1171-80.
Other Product Names
ATAD3A Antibody: ATPase family AAA domain-containing protein 3A
Tested Applications
ELISA, WB, ICC, IF
Protein ID
283436220
Physical Properties
Liquid

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