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MEIG1 Antibody

CAT: 0223-6381-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6381-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MEIG1 Antibody: MEIG1, a murine gene first identified as a testis specific gene, is a chromosome/chromatin-binding protein initially expressed during meiosis but retained in the germ cell nucleus throughout later stages of spermatogenesis. MEIG1 is a highly conserved basal metazoan gene that is indispensable for mouse spermatogenesis. It is important for normal meiotic differentiation and absolutely crucial for terminal differentiation of spermatozoa. MEIG1 encodes two alternative transcripts, designated 2a2 and 11a2, both of which encode for a common ORF but differing in their 5' untranslated region (5'UTR) due to alternative promoters.
NCBI Gene ID
644890
Swiss Prot
Q5JSS6
Accession Number
Q5JSS6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
MEIG1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1402 - Mouse Lung Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Buffer
MEIG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MEIG1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
MEIG1
NCBI Official Name
Meiosis expressed gene 1 homolog (mouse)
NCBI Organism
Homo sapiens
Background Reference 01
Don J and Wolgemuth DJ. Identification and characterization of the regulated pattern of expression of a novel mouse gene, meg1, during the meiotic cell cycle. Cell Growth Differ. 1992; 3:495-505
Background Reference 02
Salzberg Y, Eldar T, Karminsky OD, et al. Meig1 deficiency causes a severe defect in mouse spermatogenesis. Dev. Biol. 2010; 338:158-67.
Background Reference 03
Zhang Z, Shen X, Gude DR, et al. MEIG1 is essential for spermiogenesis in mice. Proc. Natl. Acad. Sci. USA 2009; 106:17055-60.
Background Reference 04
Ever L, Steiner R, Shalom S, et al. Two alternatively spliced Meig1 messenger RNA species are differentially expressed in the somatic and in the germ-cell compartments of the testis. Cell Growth Differ. 1999; 10:19-26.
Other Product Names
MEIG1 Antibody: SPATA39, bA2K17.3, Meiosis expressed gene 1 protein homolog
Tested Applications
ELISA, WB, IHC-P
Protein ID
124249370
Physical Properties
Liquid

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