Products for Research Use Only
RegisterLogin

KPNA5 Antibody

CAT: 0223-5989-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-5989-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
KPNA5 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA5 belongs to a subfamily within the KPNA family that also includes KPNA4 and 6 and is thought to be involved in NLS-dependent protein import into the nucleus.
NCBI Gene ID
3841
Swiss Prot
O15131
Accession Number
CAH71948
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
KPNA5 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 11-701 - Human Testis Tissue Slide
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rat: (81%)
Buffer
KPNA5 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
KPNA5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
KPNA5 antibody is human specific. KPNA5 antibody is predicted to not cross-react with other Importin alpha family members.
Symbol
KPNA5
NCBI Official Name
Karyopherin alpha 5 (importin alpha 6)
NCBI Organism
Homo sapiens
Background Reference 01
Moroianu J. Molecular mechanisms of nuclear protein transport. Crit. Rev. Eukaryot. Gene. Expr. 1997; 7:61-72.
Background Reference 02
Gilchrist D and Rexach M. Molecular basis for the rapid dissociation of nuclear localization signals from karyopherin alpha in the nucleoplasm. J. Biol. Chem. 2003; 278: 51937-49.
Background Reference 03
Kohler MC, Fiebeler M, Hartwig S, et al. Evidence for distinct substrate specificity of importin alpha family members in nuclear protein import. Mol. Cell. Biol. 1999; 19:7782-91.
Other Product Names
KPNA5 Antibody: SRP6, IPOA6, Importin subunit alpha-6, Karyopherin subunit alpha-5
Tested Applications
ELISA, IHC-P
Protein ID
55664992
Physical Properties
Liquid

Related Products

CatalogName
5989PKPNA5 Peptide
6655PKPNA5 Peptide
5981-01mgKPNA1 Antibody
5983-01mgKPNA2 Antibody
5981-002mgKPNA1 Antibody
46-860KPNA6 Antibody
45-813KPNA3 Antibody
5985-01KPNA3 Antibody
5991-01mgKPNA6 Antibody
26-912KPNA4 Antibody

Alternative Products

CatalogName
MBS8503833-01KPNA5 Antibody

Popular Products