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KPNA4 Antibody

CAT: 0223-26-912Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-912Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs) . Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. KPNA4 shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs) . Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
3840
Swiss Prot
O00629
Accession Number
NP_002259
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KPNA4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KPNA4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
58 kDa
Applications Notes
KPNA4 antibody can be used for detection of KPNA4 by ELISA at 1:1562500. KPNA4 antibody can be used for detection of KPNA4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KPNA4
NCBI Official Name
Karyopherin alpha 4 (importin alpha 3)
NCBI Organism
Homo sapiens
Background Reference 01
Yeung, P.L., (2008) J. Cell. Biochem. 103 (2), 456-470.
Other Product Names
KPNA4, IPOA3, MGC12217, MGC26703, QIP1, SRP3
Tested Applications
ELISA, WB
Protein ID
4504901
Physical Properties
Liquid

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