SESTD1 Antibody

• Background:

  SESTD1 Antibody: SESTD1 was initially identified in mutant zebrafish with defects in the spontaneous contraction and touch response as a novel gene, solo, encoding a protein containing SEC14 and spectrin repeat domains. Other experiments indicated that SESTD1 interacts with the TRPC4 and TRPC5, members of the transient receptor potential channel family, via the TRPC calmodulin- and inositol 1, 4, 5-triphosphate receptor-binding domain and is essential for efficient receptor-mediated activation of TRPC5, suggesting that SESTD1 is a novel regulator of these TRPC proteins.

• NCBI Gene ID:

  91404

• Swiss Prot:

  Q86VW0

• Accession Number:

  NP_835224

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  SESTD1 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1463 - Rat Brain Tissue Lysate

• Concentration:

  1 mg/mL

• Buffer:

  SESTD1 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  SESTD1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Symbol:

  SESTD1

• Positive Control 2:

  Cat. No. 10-301 - Human Brain Tissue Slide

• NCBI Official Name:

  SEC14 and spectrin domains 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sato T and Mishina M. Representational difference analysis, high-resolution physical mapping, and transcript identification of the zebrafish genomic region for a motor behavior. Genomics2003; 82:218-29.

• Background Reference 02:

  Miehe S, Bieberstein A, Arnold I, et al. The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5. J. Biol. Chem.2010; 285:12426-34.

• Other Product Names:

  SESTD1 Antibody: SOLO, SOLO, SEC14 domain and spectrin repeat-containing protein 1, Huntingtin-interacting protein-like protein

• Tested Applications:

  ELISA, WB, IHC-P, IF

• Protein ID:

  188528641

• Physical Properties:

  Liquid