VENTX Antibody

CAT: 0223-5863-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-5863-01Size:0.02 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VENTX Antibody: Lymphoid-enhancing factor/T-cell factors (LEF1/TCF) are a high-mobility group of transcriptional factors that play essential roles in cell fate determination during early embryogenesis and ontogenesis. VENTX is a member of the Vent family of homeodomain proteins. It is a novel LEF/TCF-associated transcriptional modulator. VENTX is predominately expressed in hematopoietic cells. VENTX may function as a transcriptional repressor and be involved in mesodermal patterning and hemapoietic stem cell maintenance, and has been suggested to have a potential role in the hematopoietic malignancies.
NCBI Gene ID
27287
Swiss Prot
O95231
Accession Number
NP_055283
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
VENTX Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1403 - Mouse Brain Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (92%), Chicken: (92%)
Buffer
VENTX Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
VENTX antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
VENTX
NCBI Official Name
VENT homeobox homolog (Xenopus laevis)
NCBI Organism
Homo sapiens
Background Reference 01
Reya T and Clevers H. Wnt signalling in stem cells and cancer. Nature2005; 434:843-50.
Background Reference 02
Moretti PA, Davidson AJ, Baker E, et al. Molecular cloning of a human Vent-like homeobox gene. Genomics2001; 76:21-9.
Background Reference 03
Gao H, Le Y, Wu X, et al. VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor. Cancer Res.2010; 70:202-11.
Background Reference 04
Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the β -catenin/LEF-1 pathway. Proc. Natl. Acad. Sci. USA1999; 96:5522-7.
Other Product Names
VENTX Antibody: NA88A, HPX42B, VENTX2, Homeobox protein VENTX, VENT homeobox homolog
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
7657180
Physical Properties
Liquid

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