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TCC52 Antibody

CAT: 0223-5703-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-5703-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TCC52 Antibody: Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.
NCBI Gene ID
25853
Swiss Prot
Q5T6F0
Accession Number
NP_056212
Host
Chicken
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
TCC52 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (87%)
Buffer
TCC52 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TCC52 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgY
Symbol
DCAF12
Positive Control 2
Cat. No. 17-010 - HEK293 Cell Slide
NCBI Official Name
DDB1 and CUL4 associated factor 12
NCBI Organism
Homo sapiens
Background Reference 01
Scanlan M, Simpson A, and Old L. The cancer/testis genes: review, standardization, and commentary. Cancer Immun.2004; 4:1-15.
Background Reference 02
Xia L, Li Y, Yang D, et al. Identification of new centrosome proteins by autoimmune patient sera. Sci. China C. Life Sci.2007; 50:194-202.
Background Reference 03
Li S, Hu X, Cui S, et al. Novel centrosome protein, TCC52, is a cancer-testis antigen. Cancer Sci.2008; 11:2274-9.
Other Product Names
TCC52 Antibody: CT102, TCC52, WDR40A, KIAA1892, DDB1- and CUL4-associated factor 12, Centrosome-related protein TCC52
Tested Applications
ELISA, WB, ICC
Protein ID
22218619
Physical Properties
Liquid

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Alternative Products

CatalogName
MBS150399-01TCC52 Antibody
APC00025GPolyclonal TCC52 Antibody
A11802Anti-TCC52 DCAF12 Antibody
OAPB01085-100UG-FITCTCC52 Antibody : FITC (OAPB01085-FITC)
OAPB01085-100UG-HRPTCC52 Antibody : HRP (OAPB01085-HRP)
OAPB01085-100UG-BiotinTCC52 Antibody : Biotin (OAPB01085-Biotin)
MBS152539-01TCC52 Peptide
515827WDR40A (DCAF12, DKFZp434O125, KIAA1892, TCC52, WD Repeat Domain 40A) discontinued
043831WDR40A, ID (DCAF12, KIAA1892, TCC52, WDR40A, DDB1- and CUL4-associated factor 12, Centrosome-related protein TCC52, Testis cancer centrosome-related protein, WD repeat-containing protein 40A)
146638WDR40A (DCAF12, KIAA1892, TCC52, WDR40A, DDB1-and CUL4-associated Factor 12, Centrosome-related Protein TCC52, Testis Cancer Centrosome-related Protein, WD Repeat-containing Protein 40A)

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