DCLK3 Antibody

CAT: 0223-5637-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-5637-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
DCLK3 Antibody: DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.
NCBI Gene ID
85443
Swiss Prot
Q9C098
Accession Number
NP_208382
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
DCLK3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1204 - K562 Cell Lysate
Concentration
1 mg/mL
Buffer
DCLK3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DCLK3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
DCLK3
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
Doublecortin-like kinase 3
NCBI Organism
Homo sapiens
Background Reference 01
Ohmae S, Takemoto-Kimura S, Okamura M, et al. Molecular identification and characterization of a family of kinases with homology to Ca2+/calmodulin-dependent protein kinases I/IV. J. Biol. Chem.2006; 281:20427-39.
Background Reference 02
Sossey-Alaoui K and Srivastava AK. DCAMKL1, a brain specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX), Genomics1999; 56:121-6.
Background Reference 03
Tuy FPD, Saillour Y, Kappeler C, et al. Alternative transcripts of Dlck1 and Dlck2 and their expression in doublecortin knockout mice. Dev. Neurosci.2008; 30:171-86.
Background Reference 04
Reiner O and Coquelle FM. Missense mutations resulting in type 1 lissencephaly. Cell Mol. Life Sci.2005; 62:425-34.
Other Product Names
DCLK3 Antibody: CLR, DCK3, DCDC3C, DCAMKL3, KIAA1765, Doublecortin domain-containing protein 3C
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
149589021
Physical Properties
Liquid

Related Products

CatalogName
5637PDCLK3 Peptide
5635-01DCLK2 Antibody
5633-01mgDCLK1 Antibody
5635-002mgDCLK2 Antibody
5633-002mgDCLK1 Antibody
5635-01mgDCLK2 Antibody
5633-01DCLK1 Antibody
58-134Mouse Dclk1 Antibody
5633PDCLK1 Peptide
5635PDCLK2 Peptide

Alternative Products

CatalogName
MBS8510897-01DCLK3 Antibody

Popular Products