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MIPU1 Antibody

CAT: 0223-5219-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-5219-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MIPU1 Antibody: Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.
NCBI Gene ID
63934
Swiss Prot
Q5HYK9
Accession Number
NP_071386
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
MIPU1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1301 - Human Heart Tissue Lysate
Concentration
1 mg/mL
Buffer
MIPU1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MIPU1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
ZNF667
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
Zinc finger protein 667
NCBI Organism
Homo sapiens
Background Reference 01
Jiang L, Tang D, Wang K, et al. Functional analysis of a novel KRAB/C2H2 zinc finger protein Mipu1. Biochem. Biophys. Res. Commun.2007; 356:829-35.
Background Reference 02
Wang G, Zuo X, Jiang L, et al. Tissue expression and subcellular localization of Mipu1, a novel myocardial ischemia-related gene. Braz. J. Biol. Res.2009; epub.
Background Reference 03
Yuan C, Zhang HL, Liu Y, et al. Cloning and characterization of a new gene Mipu1 up-regulated during myocardial ischemia-reperfusion. Prog. Biochem. Biophys.2004; 31:231-6.
Background Reference 04
Wang G, Zuo X, Yuan C, et al. Mipu1, a novel rat zinc-finger protein, inhibits transcriptional activities of AP-1 and SRE in mitogen-activated protein kinase signaling pathway. Mol. Cell. Biochem.2009; 322:93-102.
Other Product Names
MIPU1 Antibody: MIPU1, Zinc finger protein 667
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
38524600
Physical Properties
Liquid

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