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CPEB1 Antibody

CAT: 0223-4687-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-4687-01Size:0.02 mg
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Background
CPEB1 Antibody: CPEB1 is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly (A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF) -1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.
NCBI Gene ID
64506
Swiss Prot
Q9BZB8
Accession Number
Q9BZB8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
CPEB1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1463 - Rat Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
CPEB1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CPEB1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
CPEB1
NCBI Official Name
Cytoplasmic polyadenylation element binding protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Richter JD. CPEB: a life in translation. Trends in Biochem. Sci.2007; 32:179-85.
Background Reference 02
Jones KJ, Korb E, Kundel MA, et al. CPEB1 regulates beta-catenin mRNA translation and cell migration in astrocytes. Glia2008; 56:1401-13.
Background Reference 03
Hagele S, Kuhn U, Boning M, et al. Cytoplasmic polyadenylation element binding protein (CPEB) 1 and 2 bind to the HIF-1alpha mRNA 3'UTR and modulate HIF-1 alpha protein expression. Biochem. J.2008; epub.
Other Product Names
CPEB1 Antibody: CEBP, CPEB, CPEB-1, CPE-BP1, hCPEB-1, Cytoplasmic polyadenylation element-binding protein 1
Tested Applications
ELISA, WB
Protein ID
74762720
Physical Properties
Liquid

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