Products for Research Use Only
RegisterLogin

SAPAP1 Antibody

CAT: 0223-4623-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-4623-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SAPAP1 Antibody: SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) . SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM) .
NCBI Gene ID
9229
Swiss Prot
O60500
Accession Number
NP_004737
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
SAPAP1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1463 - Rat Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
SAPAP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SAPAP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.
Symbol
DLGAP1
Positive Control 2
Cat. No. 10-301 - Human Brain Tissue Slide
NCBI Official Name
DLG associated protein 1
NCBI Organism
Homo sapiens
Background Reference 01
SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J. Biol. Chem.1997; 272:11943-51.
Background Reference 02
Kindler S, Rehbein M, Classen B, et al. Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA. Brain Res. Mol. Brain Res.2004; 126:14-21.
Background Reference 03
Bongiorno-Borbone L, Kadare G, Benfenati F, et al. FAK and PYK2 interact with SAP/PSD-95-associated protein-3. Biochem. Biophys. Res. Commun.2005; 337:641-6.
Background Reference 04
Welch JM, Wang D, and Feng G. Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse. J. Comp. Neurol.2004; 472:24-39.
Other Product Names
SAPAP1 Antibody: DAP1; GKAP; DAP-1; SAPAP1; DLGAP1A; DLGAP1B; DAP-1-BETA; DAP-1-ALPHA.
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
4758822
Physical Properties
Liquid

Related Products

CatalogName
4623PSAPAP1 Peptide
4625-002mgSAPAP2 Antibody
4633-01SAPAP4 Antibody
4633-01mgSAPAP4 Antibody
4411-002mgSAPAP3 Antibody
4633-002mgSAPAP4 Antibody
4411-01mgSAPAP3 Antibody
4625-01mgSAPAP2 Antibody
4411-01SAPAP3 Antibody
4625-01SAPAP2 Antibody

Alternative Products

CatalogName
N0573-01SAPAP1 Antibody
JOT-AP08127-01SAPAP1 Polyclonal Antibody
BT-MCA1121-01SAPAP1 Monoclonal Antibody
75-468Anti-SAPAP1 Antibody
333425-01SAPAP1

Popular Products