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Anti-SAPAP1 Antibody

CAT: 1303-75-468Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-468Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SAPAP1 (also known as disks large associated protein 1, DAP-1, or DLGAP1) is a member of the SAPAP or DLGAP family of proteins. SAPAP1 is part of the scaffold in neuronal cells of the brain and is a component of the postsynaptic complex. SAPAP1 acts as an adaptor protein that binds synaptic scaffold proteins, cytoskeletal proteins and signaling proteins including PSD-95 and SHANK. SAPAP1 is expressed in neurons of the cortex, hippocampus and in Purkinje cells in the cerebellum. Diseases associated with DLGAP1 include Retinitis Pigmentosa 55 and Obsessive-Compulsive Disorder
Description
Our Anti-SAPAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/30. It detects human, mouse, and rat SAPAP1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Short Description
Our Anti-SAPAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N238/30. It detects human, mouse, and rat SAPAP1, and is purified by protein a chromatography. It is great for use in IHC, ICC, ELISA.
Synonyms
Disks large-associated protein 1 (SAPAP1) SAPAP-1
Gene Name
DLGAP1 DAP1 GKAP
UniProt
P97836
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (accession number P97836) produced recombinantly in E. Coli
Target
SAPAP1
Clonality
Monoclonal
Isotype
IgG1
Clone
N238/30
Type
Primary Antibody
Applications
IHC, ICC, ELISA
Field of Research
Scaffold Proteins
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Molecular Weight
110 kDa (varies due to post-translational modifications)
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity reported
Quality Control
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Rat
Conjugate
Unconjugated
IHC Quality Control
1
RRID
AB_2722668

UniProtKB · P97836

Disks large-associated protein 1

DLGP1_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P97836
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Dlgap1
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
DAP-1
EC number
—
Processing
—
Secondary accessions
O54773, P97841
Protein keywords

Technical term

3D-structureReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSynapse

PTM

PhosphoproteinUbl conjugation

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