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SAPAP4 Antibody

CAT: 0223-4633-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-4633-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SAPAP4 Antibody: SAP90/PSD-95-associated protein 4 (SAPAP4, also known as DLGAP4) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP4 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) . SAPAP4 mRNA is targeted to cell bodies in a similar manner to SAPAP1 and -2, whereas SAPAP3 mRNA is detected mainly in cell bodies.
NCBI Gene ID
22839
Swiss Prot
Q9Y2H0
Accession Number
NP_055717
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
SAPAP4 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1220 - SK-N-SH Cell Lysate
Concentration
1 mg/mL
Buffer
SAPAP4 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SAPAP4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least three isoforms of SAPAP2 are known to exist. This SAPAP4 antibody will not cross-react with other SAPAP proteins.
Symbol
DLGAP4
NCBI Official Name
Discs, large (Drosophila) homolog-associated protein 4
NCBI Organism
Homo sapiens
Background Reference 01
SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density. J. Biol. Chem.1997; 272:11943-51.
Background Reference 02
Ranta S, Zhang Y, Ross B, et al. Positional cloning and characterization of the human DLGAP2 gene and its exclusion in progressive epilepsy with mental retardation. Eur. J. Hum. Genet.2000; 8:381-4.
Background Reference 03
Kindler S, Rehbein M, Classen B, et al. Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNA. Brain Res. Mol. Brain Res.2004; 126:14-21.
Background Reference 04
Bongiorno-Borbone L, Kadare G, Benfenati F, et al. FAK and PYK2 interact with SAP/PSD-95-associated protein-3. Biochem. Biophys. Res. Commun.2005; 337:641-6.
Other Product Names
SAPAP4 Antibody: DAP4, DLP4, SAPAP4, DAP4, KIAA0964, Disks large-associated protein 4, DAP-4
Tested Applications
ELISA, WB
Protein ID
34335253
Physical Properties
Liquid

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