Products for Research Use Only
RegisterLogin

TL1A Antibody

CAT: 0223-3109-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-3109-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-κ B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI) .
NCBI Gene ID
9966
Swiss Prot
O95150
Accession Number
AAM77366
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Neuroscience
Purification
TL1A Antibody is DEAE purified.
Positive Control
Cat. No. 1216 - PC-3 Cell Lysate
Concentration
1 mg/mL
Buffer
TL1A Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TL1A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
This polyclonal antibody will not cross-react with TL1.
Symbol
TNFSF15
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 15
NCBI Organism
Homo sapiens
Background Reference 01
Chinnayan AM, O'Rourke K, Yu GL, et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996; 274:990-2.
Background Reference 02
Kitson J, Raven T, Jiang YP, et al. A death-domain-containing receptor that mediates apoptosis. Nature 1996; 384:372-5.
Background Reference 03
Screaton GR, Xu XN, Olsen AL, et al. LARD: a new lymphoid-specific death domain containing receptor regulated by pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 1997; 94:4615-9.
Background Reference 04
Bodmer JL, Burns K, Schneider P. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95) . Immunity 1997; 6:79-88.
Other Product Names
TL1A Antibody: TL1, TL1A, VEGI, VEGI192A, TL1, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1
Tested Applications
ELISA, WB
Protein ID
21745392
Physical Properties
Liquid

Related Products

CatalogName
3109PTL1A Peptide
11-109TL1A / TNFSF15 Recombinant Protein
33-425Cytokeratin 7 Antibody [OV-TL12/30]
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody

Alternative Products

CatalogName
MBS535934-01TL1A antibody
APR06400GPolyclonal TL1A Antibody
32653-05111Human TL1A Antibody
GWB-5851DETL1A Antibody (N-term)
MBS1750765-01Anti-TL1A Picoband antibody
101729-2Anti-TL1A Neutralizing Antibody
V5302-20UGTNFSF15 Antibody / VEGI / TL1A
RQ4107TL1A Antibody / TNFSF15 / VEGI
V7227-20UGTL1A Antibody / VEGI / TNFSF15
GTR18225914TNFSF15/TL1A/VEGI Antibody

Popular Products