SODD Antibody

CAT: 0223-2143-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-2143-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
SODD Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.
NCBI Gene ID
9530
Swiss Prot
O95429
Accession Number
AF111116
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
SODD Antibody is DEAE purified.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/ml
Buffer
SODD Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SODD antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
IgG
Symbol
BAG4
Positive Control 2
Cat. No. 1208 - THP-1 Cell Lysate
Positive Control 3
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
BCL2-associated athanogene 4
NCBI Organism
Homo sapiens
Background Reference 01
Jiang Y, Woronicz JD, Liu W, Goeddel DY. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. Science 1999;283:543-6 (RD1299)
Other Product Names
SODD Antibody: SODD, BAG-4, SODD, BAG family molecular chaperone regulator 4, Bcl-2-associated athanogene 4
Tested Applications
ELISA, WB, ICC, IF
Protein ID
4160013
Physical Properties
Liquid

Related Products

CatalogName
2143PSODD Peptide
63-616SOD1 Antibody
14-969SOD2 Antibody
63-009SOD2 Antibody
15-275SOD3 Antibody
22-606SOD3 Antibody
13-120SOD1 Antibody
30-113SOD1 Antibody
42-387SOD2 Antibody
46-412SOD1 Antibody

Alternative Products

CatalogName
R34112-100UGSODD Antibody
STJ71776Anti-SODD antibody
APR06251GPolyclonal SODD Antibody
MB11595SODD monoclonal antibody
TMAB-13034-01Anti-SODD Polyclonal Antibody
MBS668784-01Polyclonal Antibody to SODD/BAG4
SL10774R-01Rabbit Anti-SODD antibody
PAab08106Anti-SODD/BAG4 antibody
2143Anti-SODD (NT) Antibody
MBS422187-01Goat anti-SODD Antibody

Popular Products