SOD2 Antibody

CAT: 0223-14-969Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-14-969Size:100 µL
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Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
NCBI Gene ID
6648
Swiss Prot
P04179
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
K-562
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 23kDa
Fragment
IgG
Symbol
SOD2
Positive Control 2
HepG2
Positive Control 3
DU145
Positive Control 4
U-251MG
Positive Control 5
Mouse kidney
Positive Control 6
Mouse liver
NCBI Official Name
Superoxide dismutase 2, mitochondrial
NCBI Organism
Homo sapiens
Other Product Names
Superoxide dismutase [Mn], mitochondrial, manganese-containing superoxide dismutase, indophenoloxidase B, Mn superoxide dismutase, MVCD6, MNSOD, IPOB, RP1-56L9.2, superoxide dismutase 2, SOD2
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

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