SOD2 Antibody

• Background :

  This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

• NCBI Gene ID :

  6648

• Swiss Prot :

  P04179

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 25-222 of human SOD2 (NP_000627.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  K-562

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 23kDa

• Fragment :

  IgG

• Symbol :

  SOD2

• Positive Control 2 :

  HepG2

• Positive Control 3 :

  DU145

• Positive Control 4 :

  U-251MG

• Positive Control 5 :

  Mouse kidney

• Positive Control 6 :

  Mouse liver

• NCBI Official Name :

  Superoxide dismutase 2, mitochondrial

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Superoxide dismutase [Mn], mitochondrial, manganese-containing superoxide dismutase, indophenoloxidase B, Mn superoxide dismutase, MVCD6, MNSOD, IPOB, RP1-56L9.2, superoxide dismutase 2, SOD2

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid